Forced Cough Vocalization & Innovation in Respiratory Wellness

RAIsonance harnesses the power of artificial intelligence to achieve a range of health-related outcomes. We specialize in the analysis of Forced Cough Vocalizations (FCV), intentional coughs that are a rich source of biometric and biomarker data. Our advanced technology enables us to detect physical changes and specific diseases by analyzing this data. Through the use of FCV analysis, we are able to provide valuable health insights and contribute to improving overall wellness.

FCV Signature Analysis

Tracking FCV Wellness

RAIsonance has developed technology that detects, analyzes, and tracks changes to respiratory function. Simply put, the user establishes a “baseline” which is a snapshot of their respiratory system. Each individual’s FCV profile is totally unique to them, just like a fingerprint or retina scan. Once the baseline has been created our FCV analysis technology can identify the tiniest of changes by comparing current coughs to the individual’s baseline profile.

To create a complete biometric FCV profile — also called the baseline — users submit a seriesof intentional coughs over an established period of time. After downloading our app onto their phone, the user is taken through the process of coughing into the mobile app. Those cough sounds go to the cloud for analysis, and the resulting group of data points becomes the user’s baseline FCV signature. Once a baseline is established, the user can cough into the mobile app again anytime, and the system rapidly compares the new cough to the established baseline. Results are delivered in about 2 minutes.

FCV analysis can be used in many ways. It can track improvement, and it can detect negative changes that may be the result of exposure to a pathogen, chemical agent, or environmental toxin. FCV analysis can also detect certain diseases and conditions, and monitor progression and status of respiratoryrelated conditions. We call this our FCV Wellness Technology, and we’ve incorporated it into three product lines.

MyAdvocate

Tracking Symptoms and Experiences with Specific Conditions

MyAdvocate uses the same technology as Sentinel but is designed to help individuals track ongoing conditions. MyAdvocate also includes a customized symptom diary to help the user document their experiences and provide data-rich reporting. Users can track symptoms for themselves or share their diary with healthcare providers or family members.

The MyAdvocate line currently includes versions for:

  • Long COVID sufferers, tracking ongoing dysfunction and severity. After creating their baseline, the user can cough again and receive an FCV Impairment Score. They can document their symptoms and see trends and patterns in the course of their illness.
  • For smokers, MyAdvocate Smoker Recovery starts with a user's profile once they’ve decided to quit. Then it tracks the smoker's journey from being a smoker, providing an FCV Improvement Score that shows their progress over time.
  • For users that have decided to quit vaping, MyAdvocate Vape Recovery aunctions similarly to Smoker Recovery.

Learn More About MyAdvocate Products

FCV Sentinel

Detecting Changes to FCV Wellness

FCV Sentinel functions as an early warning system. It does not indicate what caused any changes it detects. Instead it notifies the user that changes have been detected and should be reviewed. The changes may be caused by various things such as a disease, or exposure to chemical agents or environmental toxins. Any of these can produce a notable change in the user’s FCV and be reflected in their FCV score. Higher scores – between 80 and 99 – tell the user that little or no change has been detected. Scores between 50 and 79 indicate that a notable difference has been detected. Scores below 50 indicate a significant change that may warrant a health work up. This digital wellness product is designed to support both individuals tracking their own FCV status, and also for groups such as large employers, colleges and universities, and airline or cruise ship passengers. While FCV Sentinel does not diagnose any conditions or distinguish between pathogens and chemical agents, it is designed to provide fast, biometric, early warning signal for any user.

Learn More About FCV Sentinel

Biometric Soundpass

Detecting Changes to FCV Wellness with Alerts & Passcodes

SoundPass operates like a “check engine” light, alerting the user that an out-ofrange change has been detected. This provides a “first alert” signal. In some specialized use cases it also creates a scannable QR code.

This respiratory wellness app combines the reliability of biometrics with the precision and scalability that only an advanced AI/ML-based technology can deliver. With SoundPass, individuals, workplaces, businesses, places of worship, government offices, and education campuses can curb the spread of illness with better, smarter tools.

Learn More About Biometric SoundPass

Audible Health AI

FCV Analysis for Respiratory Disease Screening

The AudibleHealth AI screening platform uses advanced AI models to identify individuals who are likely to have active infections with specific diseases by analyzing their coughs. The RAIsonance Clinical Decision Support solution helps determine whether an individual should undergo more definitive diagnostic testing, such as a chest X-ray, sputum smear, microscopy, or molecular tests such as the Cepheid GeneXpert for MTB/RIF for TB, or other RT-PCR systems for various respiratory conditions.

Respiratory-related illnesses create specific disease signatures or patterns in the thousands of data points collected in each cough sample. This is due to the unique ways in which each disease affects the human respiratory system. Some diseases create additional mucus, cause changes in mucus viscosity, cause varying inflammation and cough harmonics, or produce conditions like airway constriction. By collecting many coughs from subjects who are confirmed positive for a specific disease and many coughs from people who are confirmed negative, AudibleHealth AI data scientists train AI/ML models that detect the specific patterns correlated to the target disease positives or negatives.

To use the solution, patients cough for 10 seconds into the AudibleHealth app on their smartphone. Once captured the app sends the cough sample to our cloud-based analysis environment, and results are returned to the user in around 30 seconds.

To date the company has developed tests on the platform for COVID-19 and Tuberculosis, and is finishing clinical trials for Influenza and Pneumonia. It has also developed a solution for the insurance underwriting industry which identifies whether an individual is cigarette smoker. The product roadmap includes the addition of test types for another 15 to 20 respiratory conditions including measles, pertussis, pneumonia, lung cancer, emphysema, and congestive heart failure, on this unique digital screening platform.

Learn More About AudibleHealth AI

To Learn More about the Science Behind FCV Wellness Technology, Download the Complete Report >

“The convenience of this FCV-based Wellness and Screening technology is unsurpassed. The rigorousness and reliability of these products is also unsurpassed, making this modality a valuable, trusted technology in healthcare.”

Liz Maxwell-Schmidt
MS, MD, FAAEP, FACEPMD

President of the American Association
of Physician Specialists

Audible Health AI

AudibleHealth AI respiratory screening software was developed in part with a contract from BARDA to detect COVID-19 and Influenza.

Read more about this project >

“Our mission is to have a meaningful, positive impact on global respiratory health with these innovative, inexpensive, scalable solutions. Using a non-invasive smartphone app to collect a cough sound for screening creates accessible, convenient solutions which we’re bringing all over the world.”

Kitty Kolding
CEO & Co-Founder

RAIsonance Group of Companies